PCOS
(polycystic ovarian
syndrome)

What is PCOS?

PCOS (Polycystic Ovary Syndrome) is a condition where the ovaries produce an unusual amount of a hormone called androgen in the body, which under normal circumstances is present in traces in women and happens usually during the reproductive years. PCOS  defines various small cysts (fluid-filled sacs) that form in the ovaries. The formation of cysts is not confirmatory for this disorder, as some women without this disorder have cysts.

In a number of cases, a woman is not able to produce enough hormones for ovulation.  When ovulation does not take place, there are chances of the ovaries developing various small cysts. These cysts produce a hormone called androgen, which is one of the reasons why women with PCOS often have higher amounts of androgen. This results in more difficult menstruation and may cause various symptoms of PCOS.

Causes of Polycystic Ovarian Syndrome

causes of pcos

The exact cause is still unknown for PCOS, but there is some evidence pointing towards genetics as one of the causative factors.

 

Other significant factors include:

  • Increased levels of androgen (male hormone): A high level of androgen inhibits the release of eggs from the ovaries (i.e., ovulation), which leads to an irregular menstrual cycle. Irregular ovulation can also cause cysts to develop in the ovaries. Increased levels of androgen cause acne and excess hair growth in women.

  • Resistance to insulin: Increased levels of insulin cause the ovaries to produce irregular ovulation and other symptoms of PCOS.  High insulin levels when blood sugar levels are normal can indicate insulin resistance.

  • Low grade inflammation: People with PCOS are more likely to have chronic low-grade inflammation. A blood test will be performed to check levels of C-reactive protein and WBCs, which can indicate inflammation levels in the body.

Symptoms pertaining PCOS

  • Irregular menstruation: An irregular period is defined as a missed period or a period that does not occur at all. Heavy bleeding during periods can also be a symptom of PCOS.

  • Excessive hair growth: excessive hair on the face, arms, chest, and abdomen is also known as hirsutism and is seen in more than 70 percent of PCOS-affected women.

  • Acne : PCOS can cause acne especially affecting back ,chest and face and may continue even after puberty years and is hard to treat .

  • Obesity: More than 80% of women with PCOD are obese and  can lose weight only with extreme difficulty.

  • Skin darkening: Patches of dark skin are seen in some specific areas like the neck folds, armpit, ,groyne and underside of the breast. This skin condition is known as Acanthosis Nigricans.

  • Cysts: These are small sacs of fluid that develop along the outer edge of the ovary.

  • Thinning of Hair: Male pattern baldness or patchy baldness is seen in persons with PCOS, i.e., they tend to lose hair or go bald.

  • Infertility: PCOS is among the most common reasons for infertility in women.  Decreased ovulation or the absence of ovulation may result in failure to conceive.  In a normal cycle, one egg matures and is released every month, while in the case of PCOS, all follicles remain small throughout the cycle, thus preventing egg release, known as ovulatory dysfunction.

symptoms of pcos

Detection of PCOS

detection of pcos

Detection of PCOS is done by a combination of various investigations, including blood tests and imaging. Symptoms and medical history play a very important role in its diagnosis.

  • Clinical history:
    includes symptoms of affected individuals as well as their onset, such as irregular periods, weight that cannot be lost despite consistent efforts, excessive hair growth, etc.  eacne, for example
    Eating and drinking habits, and any medication intake, including supplements and vitamin tablets.
  • Physical examination: It consists of a pelvic examination, which checks the health of the reproductive organ both inside and outside for any mass, growth, or abnormality.
  • Imaging:  Ultrasound is done to check the size of the ovaries and check for cysts.  It can also be used to know thickness of uterus
  • Blood tests: Blood tests are done usually to check- hormone levels ( androgen in. male hormone levels is elevated )
  • fastinglipid profile glucose tolerance tests ( to check insulin resistance )      Other tests include Regular  BP monitoring, screening for anxiety and depression, and screening for obstructive sleep apnea. 

Confirmatory Diagnosis of PCOS

 Minimum presence of at least two of following-

  • People with PCOS may have irregular or missed periods, as well as heavy bleeding during their periods.
  • Clinical signs and symptoms of excess androgen, like acne or excessive hair growth  or a confirmatory blood test for excess androgen levels.
  • Cysts on one or both ovaries It is not seen in many people.

PCOS & PCOD – Different or Same

There are both similarities and differences between PCOS and PCOD.

Some similarities are-

  • Both are medical conditions affecting the ovaries and causing hormonal imbalance.
  • Age predilection is same i.e.. reproductive age

Same symptoms

Differences between PCOS and PCOD :

Factors

PCOD

PCOS

Prevalence

It is a common disorder affecting 10 % of women population in the world

It is serious medical condition affecting 0.2 to 2.5 % of women population in world

Cause

It is a condition in which the ovary produces various immature or partially mature eggs.  It’s causative factors  are poor lifestyle, stress, obesity ,stress and  imbalance of hormones

It is metabolic disorder and more severe and complicated form of PCOD ,can lead to anovulation where ovaries do not release egg

Fertility

It does not affect fertility in women to greater extent as women can still ovulate and can get pregnant with some aid and by following proper medication can complete pregnancy

It seriously affects fertility in women.  As due to irregular ovulation ,getting pregnant itself is challenge and if got pregnant then there is risk of miscarriage ,premature birth and many other complications in their pregnancy

Complications

No serious complications are related to PCOD

Complications  are type 2 diabetes, heart disease, high BP and endometrial cancer in later stage

 

PCOS –Major Cause for Women Infertility

PCOS can be simply understood as being directly linked with infertility because the PCOS ovulation process itself is improper, which hinders the ovary from getting the desired level of hormone necessary for ovulation. It leads to irregular periods and also causes infertility.

Some women with PCOS may release mature eggs occasionally, but in others there is a complete absence of ovulation. To conceive, fertilization takes place between sperm and a mature egg; ovulation becomes the primary requirement to get pregnant.

PCOS & Pregnancy

Women with PCOS have difficulty conceiving as well as an increased risk of complications during pregnancy. The majority of females with PCOS become pregnant; they take longer to get pregnant and often need fertility treatment in comparison to women without PCOS.

Adopting a healthy lifestyle, including a healthy weight range, a healthy diet, regular exercise, no smoking or drinking, enough sleep, and a stress-free environment, increases the chances of pregnancy and having a healthy baby.

For overweight women with PCOS, modest weight loss in some cases, lead to regular ovulation.

When Should You Seek Medical Help?

 Seek medical advice when you tried for a baby for 12 months without success ,if age above 35 time window decreases to six months.

In case of sporadic or irregular periods, an indication that ovulation is not taking place and needs medical help to get pregnant. The first line of treatment is ovulation induction, which involves a course of tablets or injections to stimulate the ovary for the release of an egg that can be fertilized either during intercourse or through IUI.

If none of the above methods work, a more invasive method such as IVF is required.

The IVF procedure includes a number of injections to stimulate the ovary for the production of multiple eggs. Once mature, the eggs are retrieved in an ultrasound-guided procedure, and sperm is added for the lab formation of embryos.

After a few days, the embryo is placed in the uterus, where it may implant and grow into a baby.  In an IVF procedure, there are more chances that two embryos, or womb embryos,wembryos,can be frozen for later use if there is no pregnancy.

Beware of some possible health effects like ovarian hyperstimulation syndrome, which is an overreaction to fertility drugs used to stimulate the ovaries for the production of multiple eggs. It can lead to nausea, vomiting, abdominal pain, blood clots, and rapid weight gain.

Pregnancy Complications in PCOS: 

It includes preeclampsia (a condition in pregnancy characterized by high blood pressure, sometimes with fluid retention and proteinuria), which is dangerous for both mother and fetus. Other complications include pregnancy-induced hypertension (high blood pressure) and gestational diabetes.

Gestational diabetes can lead to having a larger-than-average baby, which may cause complications during delivery like shoulder dystocia (when the baby’s shoulder gets stuck during labor).

Most PCOS symptoms during pregnancy are treatable with careful monitoring. In cases of gestational diabetes, insulin may be required to maintain blood sugar levels. 

PCOS Treatment –

Treatment of PCOS depends on various factors and differs from individual to individual.  Some factors are age, symptoms, and overall health; it also depends on whether one is willing to get pregnant or not.

If one is planning to get pregnant, possible treatment options are:

  • Lifestyle Change
  • Dietary modification
  • Ovary stimulation with use of medication
  • Invasive treatment like IVF 
  • If pregnancy is not a concern:
  • Birth control pills
  • Diabetes medication
  • A change in lifestyle and diet
  • Medications for symptoms – specific medications for symptom relief like acne or hair loss etc.

Frequently Asked Questions

Couples who cannot conceive a baby naturally due to medical reasons can opt for surrogacy. Surrogacy makes it possible for them to welcome parenthood and realize their dream of having their own child. Moreover, the success rate of surrogacy is also high.

Mothers Worlds is the best surrogacy clinic in Delhi. We are a professional surrogacy clinic with immense experience and expertise. We have helped several intending couples welcome their bundle of joy. Our surrogacy price in Delhi is reasonable and includes the entire surrogacy process. We work closely with couples and surrogates and keep a close watch on the progress. We aim to provide a hassle-free, pleasant journey for couples as well as the surrogate. Our premises are well-planned and equipped. We have a dedicated team for personal assistance, especially for surrogacy patients. For the best-in-class fertility and surrogacy treatments, connect with our team now.

Surrogacy helps families with infertility to conceive a baby. Surrogacy helps couples with some genetic defects who don’t wish to pass it on to their children. It also enables couples to genetically link up with the baby.

here is a lot of legal, emotional, and physical preparation that one needs to do in order to prepare oneself for the surrogacy process. The couple also needs to consider various social aspects before commencing the surrogacy process. 

Our patient-friendly approach, economical surrogacy package, and strategic surrogacy services make us the best surrogacy clinic in India. We have a team of dedicated professionals to assist surrogacy patients and help couples throughout the surrogacy process.

Please make sure we do not make false claims. The government is quite strict against all such claims in the fertility sector.

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